Generalized theory for current-source-density analysis in brain tissue
نویسندگان
چکیده
منابع مشابه
Generalized theory for current-source-density analysis in brain tissue.
The current-source density (CSD) analysis is a widely used method in brain electrophysiology, but this method rests on a series of assumptions, namely that the surrounding extracellular medium is resistive and uniform, and in some versions of the theory, that the current sources are exclusively made by dipoles. Because of these assumptions, this standard model does not correctly describe the co...
متن کاملA generalized theory for current-source density analysis in brain tissue
The current-source density analysis is a widely used method in brain electrophysiology, but this method rests on a series of assumptions, namely that current sources are exclusively made by dipoles, and that the surrounding medium is resistive and uniform. Because of these assumptions, this standard model cannot be used to estimate the contributions of monopolar sources or of non-resistive aspe...
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Current Source Density analysis (CSD) is a class of methods of analysis of extracellular electric potentials recorded at multiple sites leading to estimates of current sources generating the measured potentials. It is usually applied to low-frequency part of the potential (called the Local Field Potential, LFP) and to simultaneous recordings or to recordings taken with fixed time reference to t...
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This article provides a theoretical basis for relating macroscopic electrical signals recorded from biological tissue, such as electroencephalogram (EEG) and local field potential (LFP), to the electrophysiological processes at the cellular level in a manner consistent with Maxwell’s equations. Concepts of the apparent extracellular current density and the apparent extracellular space with appa...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2011
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.84.041909